Anabolic Steroid-induced Mania

Anabolic androgenic steroid-induced hepatotoxicity.

Anabolic androgenic steroids (AAS) have been abused for decades by both professional and amateur athletes in order to improve physical performance or muscle mass. AAS abuse can cause adverse effects, among which are hepatotoxic effects. These effects include cholestatic icterus and possibly peliosis hepatis and hepatocellular carcinoma or adenoma. In particular, 17α-alkylated AAS appear to be h...

Steroid-induced mania treated with aripiprazole.

Brown and Chandler reviewed the literature on significant psychiatric side effects of corticosteroids, noting presentations of depression, mania, psychosis, and memory deficits. Naber et al. followed a prospective, uncontrolled cohort of 50 patients on methylprednisolone or fluocortolone, at initial doses of 119 41 mg/d, and tapered to 75 22 mg/d over 8 days. They found that “manic-type” sympto...

Anabolic steroid-induced hypogonadism--towards a unified hypothesis of anabolic steroid action.

Anabolic steroid-induced hypogonadism (ASIH) is the functional incompetence of the testes with subnormal or impaired production of testosterone and/or spermatozoa due to administration of androgens or anabolic steroids. Anabolic-androgenic steroid (AAS), both prescription and nonprescription, use is a cause of ASIH. Current AAS use includes prescribing for wasting associated conditions. Nonpres...

Anabolic steroid induced acute myocardial infarction

Androgenic anabolic steroids are commonly abused by athletes and body-builders to help develop lean body mass and muscular strength to enhance their performance. However, at doses which are much higher than recommended therapeutic dosage, abuse of these drugs is commonly associated with cardiovascular side-effects that can lead to acute myocardial infarction and sudden death. We report here thr...

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